The choices of colors and materials further enhance the impression of personal luxury and the interior's interplay of lines and surfaces. For the dash's finely grained upper section, there are two colors depending upon the chosen interior color. Dakota leather is standard on the 550i, and available in six color schemes of which three are new; BMW's luxurious Nappa leather is optional, and available in three color schemes.

Dark Burl Ash wood trim interior trim is standard, appearing in sweeping expanses on the dash, doors and front center console; Ash Anthracite (gray tone) and another distinctive wood called Fineline Matte are optional.

The center console comes in two variants: On cars with a manual gearbox the console is split into two sections, the black surface surrounding the gearshift lever and the buttons on the optional Driving Dynamics Control oriented towards the driver. A key holder has been placed between the gearshift lever and the climate controls.

On models with automatic transmission, the space between the electronic gear selector lever and the climate control unit offers enough room for two cupholders and a key holder. A further storage compartment is located behind the iDrive Controller (where there is another cupholder on models with a manual gearbox).